Cosmate®SQE Squalene was initially extracted from the liver of deep-sea sharks. In fact, squalene is not only present in shark liver, but also distributed in many plants, but its content is not high. Most of it is less than 5% of unsaponifiable substances in plant oil, and a few have a higher content. For example, the content of squalene in wild jasmine seed oil is higher, exceeding that in olive oil and rice bran oil. In addition, squalene is also widely distributed in our body's skin, subcutaneous fat, liver, nails, brain and other organs. It participates in cholesterol synthesis and various biological reactions in the body to promote metabolism and operation, and improve the body's resistance and defense capabilities; In other words, squalene is involved in body metabolism and cellular biochemical reactions in the body.
Squalene is a naturally occurring lipid found in human sebum, plants, and animals. It is a key component of the skin’s lipid barrier, playing a vital role in maintaining hydration and protecting against environmental stressors. Traditionally sourced from shark liver oil, modern production methods now focus on plant-based sources (e.g., olive oil, amaranth seed oil) and biotechnological processes to ensure sustainability and ethical standards. While squalene is highly effective in skincare, it is less stable than its hydrogenated form, squalane, due to its susceptibility to oxidation.
Squalene Key Functions
Deep Moisturization:Squalene acts as a natural emollient, helping to lock in moisture and improve skin elasticity.
Antioxidant Protection:Squalene neutralizes free radicals caused by UV radiation and pollution, reducing oxidative stress and premature aging.
Skin Barrier Reinforcement:Squalene strengthens the skin’s natural lipid barrier, enhancing its ability to retain moisture and defend against irritants.
Wound Healing and Regeneration:Squalene promotes skin repair and regeneration, making it ideal for damaged or aging skin.
Enhanced Absorption:Squalene facilitates the penetration of other active ingredients, improving their efficacy.
Squalene Mechanism of Action
Squalene works by integrating into the stratum corneum due to its molecular similarity to the skin’s natural lipids, filling gaps between skin cells and restoring smoothness. It forms a breathable, protective layer that locks in moisture while allowing the skin to breathe. Additionally, squalene acts as an antioxidant, scavenging free radicals and reactive oxygen species (ROS) to prevent cellular damage and oxidative stress. It also enhances the penetration and effectiveness of other active ingredients, such as vitamins and retinoids, through synergistic delivery.
Squanlene benefits and Advantages
Biocompatibility:Naturally present in human sebum, making it highly compatible with all skin types, including sensitive skin.
Versatility:Suitable for a wide range of skincare products, including moisturizers, serums, sunscreens, and cleansers.
Anti-Aging Benefits:Improves skin elasticity, reduces fine lines, and promotes a youthful appearance.
Sustainability:Plant-derived and biotech-produced squalene are eco-friendly and align with vegan and cruelty-free trends.
Synergy with Actives:Enhances the performance of other bioactive ingredients while reducing potential irritation.
Appearance |
Light yellow to colorless transparent liquid |
Odor |
Mid characteristic |
Total Squalene Content |
≥70.0% |
Iodine Value |
280~330g/100g |
Acidity |
≤1.0ml |
Appearance |
Light yellow to colorless transparent liquid |
Odor |
Characteristic |
Density @20℃ (g/ml) |
0.845-0.865 |
Refractive Index @20℃ |
1.4945-1.4980 |
Acid Value (mg KOH/g) |
≤1 |
Iodine Value (gl2/100g) |
360-400 |
Saponification Value (mg KOH/g) |
≤1 |
Peroxide Value (meq/kg) |
≤5 |
Gas Chromatography (%) |
≥99 |
Arsenic (ppm) |
≤0.1 |
Cadmium (ppm) |
≤0.1 |
Lead (ppm) |
≤0.1 |
Mercury (ppm) |
≤0.1 |
Dioxins + DL PCB’S (pg(WHO TEQ/g) |
≤6.0 |
Dioxins (pg(WHO TEQ/g) |
≤1.75 |
NDLPCB’S (ng/g) |
≤200 |
PAH's (benzo(a)pyrene) (μg/kg) |
≤2 |
Total PAH's (μg/kg) |
≤10 |
E. Coli & Salmonella |
Negative |
Coliforms and S.aureus |
Negative |