Anti-aging Silybum marianum extract Silymarin

Silymarin is a serious weapon, and it is a natural flavonoid lignan compound derived rigorously and directly from the dried fruit of the "milk thistle," the plant mostly considered the most important in this Asteraceae family. The potent extract has been primarily built with silybin, isosilybin, silydianin, and silychristin, Silymarin a strong health agent. Silymarin has solubility properties unique to it-it is very soluble in acetone, ethyl acetate, methanol, and ethanol, somewhat soluble in chloroform but not soluble in water. If you want to improve your health the natural way, look no further - Silymarin.

This herb is also quite famous among ancient Greeks and Romans as an antidote to snake bites. The active ingredients are turned and modernized for skin care. This advanced extract had the most concentrated silymarin, beneficial in skin disorders, moisturizing, providing pollution resistance, and reducing fine lines and wrinkles. Transform your daily government applications with NE Milk Thistle Cellular Extract, and reap the benefits from this ancient magical potion. Silymarin 80% is a premium milk thistle extract that contains 80% silymarin as the standard. Silymarin in medicinal circles is known for its very strong antioxidant properties coupled with the important flavonoids silybin, silydianin, and silychristin. Silymarin has been lauded through the ages, Silymarin 80% for liver health, contributing to the detoxification and function of the liver. This good extract serves as an alternative option towards providing good liver support while also dealing with oxidative damage. Silymarin 80%- go with the gift of nature. Silymarin is a flavonoid complex extracted from the seeds of the milk thistle plant (Silybum marianum). It is composed of several active compounds, including silybin, silydianin, and silychristin, with silybin being the most potent. Silymarin is renowned for its antioxidant, anti-inflammatory, and skin-protective properties. It is widely used in skincare to combat oxidative stress, soothe irritation, and support skin repair. Its ability to protect against UV-induced damage and promote collagen synthesis makes it a valuable ingredient in anti-aging and protective skincare formulations.

Key Functions

1. Antioxidant Protection: Neutralizes free radicals caused by UV radiation and environmental pollutants, preventing oxidative damage and premature aging.
2. Anti-Inflammatory Effects: Reduces redness, swelling, and irritation, making it suitable for sensitive or inflamed skin.
3. UV Damage Protection: Helps mitigate the harmful effects of UV exposure, including photoaging and DNA damage.
4. Collagen Synthesis Support: Promotes collagen production, improving skin elasticity and reducing the appearance of fine lines and wrinkles.
5. Skin Barrier Repair: Enhances the skin’s natural barrier function, improving hydration and resilience.

Mechanism of Action

Silymarin works by scavenging free radicals and reducing oxidative stress through its potent antioxidant activity. It inhibits inflammatory pathways, such as NF-κB and COX-2, to reduce redness and irritation. Additionally, silymarin protects skin cells from UV-induced damage by preventing DNA degradation and collagen breakdown. It also stimulates collagen synthesis and supports the skin’s natural repair processes, enhancing barrier function and overall skin health.

Advantages

1. Multifunctional: Combines antioxidant, anti-inflammatory, and anti-aging benefits in a single ingredient.
2. UV Protection: Provides additional defense against UV-induced damage, complementing sunscreen efficacy.
3. Suitable for Sensitive Skin: Gentle and non-irritating, making it ideal for reactive or inflamed skin.
4. Natural Origin: Derived from milk thistle, aligning with consumer preferences for plant-based and sustainable ingredients.
5. Stable Formulation: Compatible with a wide range of skincare products, including serums, creams, and sunscreens.

Applications

1. Anti-Aging Products: Reduces fine lines, wrinkles, and photoaging by promoting collagen synthesis and protecting against oxidative stress.
2. Soothing Creams: Calms redness and irritation in sensitive or inflamed skin.
3. Sunscreens: Enhances UV protection and prevents photoaging.
4. Repair Serums: Supports skin barrier repair and hydration in post-procedure or damaged skin treatments.
5. Daily Moisturizers: Improves overall skin health and resilience while protecting against environmental stressors.

Technical Parameters:

Appearance	Amorphous Powder
Colour	Yellow to Yellowish-Brown
Odour	Slight, Specific
Solubility
- in Water	Practically Insoluble
- in Methanol and Acetone	Soluble
Identification	Thin-Layer Chromatographic Identification Test HPLC Identification Test
Sulphated Ash	NMT 0.5%
Heavy metals	NMT 10 PPM
- Lead	NMT 2.0 PPM
- Cadmium	NMT 1.0 PPM
- Mercury	NMT 0.1 PPM
- Arsenic	NMT 1.0 PPM
Loss On Drying (2 Hours 105 ℃)	NMT 5.0%
Powder size
Mesh 80	NLT100%
Assay of Silymarin (UV test, per cent, Standard in House)	Min. 80%
Residual Solvents
- N-hexane	NMT 290 PPM
- Acetone	NMT 5000 PPM
- Ethanol	NMT 5000 PPM
Pesticide Residues	USP43<561>
Microbiological Quality (Total viable aerobic count)
- Bacteria, CFU/g, not more than	103
- Moulds and yeasts, CFU/g, not more than	102
- E.coli, Salmonella, S. aureus, CFU/g	Absence

Functions: *Maintains skin elasticity by fighting glycation *Reduces wrinkles and lines *Increases skin firmness *Protects skin cells from oxidative aging Applications: *Antioxidant *Anti-inflammatory *Brightening *Wound Healing *Anti-photoaging